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骨科创伤中的异位骨化。

Heterotopic ossification in orthopaedic trauma.

机构信息

Department of Surgery, Division of Orthopaedics, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

出版信息

J Orthop Trauma. 2012 Dec;26(12):684-8. doi: 10.1097/BOT.0b013e3182724624.

Abstract

Heterotopic ossification (HO) can be defined as the pathologic formation of bone in extraskeletal tissues. There has been a substantial amount of recent research on the pathophysiology, prophylaxis, and treatment of HO and traumatic conditions associated with the development of HO. This research has advanced our understanding of this disease and helped to clarify evidence-based approaches to both the prophylaxis and treatment of HO. This article reviews the literature on these topics with a focus on their application in orthopaedic trauma.

摘要

异位骨化(HO)可定义为在骨骼外组织中病理性形成骨。最近有大量研究涉及 HO 的病理生理学、预防和治疗以及与 HO 发展相关的创伤性疾病。这些研究加深了我们对该疾病的认识,并有助于阐明 HO 的预防和治疗的循证方法。本文综述了这些主题的文献,重点介绍其在骨科创伤中的应用。

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