Division of Clinical Dermatology, Department of Systematic Pathology, University of Naples Federico II, Napoli, Italy.
Dermatitis. 2012 Sep-Oct;23(5):237-8. doi: 10.1097/DER.0b013e31826e45d7.
A wide spectrum of skin toxicities has been described in patients receiving epidermal growth factor receptor (EGFR), inhibitors, including papulopustular rash, xerosis and fissures, pruritus, mucositis, paronychia, and hair changes.Trichomegaly of the eyelashes is a rare adverse effect of EGFR inhibitor therapy and is characterized by a paradoxical overgrowth of eyelashes. We present 3 cases of trichomegaly occurred during EGFR inhibitor therapy.
接受表皮生长因子受体（EGFR）抑制剂治疗的患者会出现广泛的皮肤毒性反应，包括脓疱性皮疹、皮肤干燥和皲裂、瘙痒、黏膜炎、甲周病和毛发变化。睫毛增粗是 EGFR 抑制剂治疗的罕见不良反应，其特征是睫毛异常过度生长。我们报告了 3 例在 EGFR 抑制剂治疗期间发生的睫毛增粗病例。
