Department of Chemistry & Chemical Biology, University of New Mexico, MSC03 2060, Albuquerque, NM 87131-0001, USA.
Chem Commun (Camb). 2012 Nov 7;48(86):10669-71. doi: 10.1039/c2cc35602c.
A new internal charge transfer (ICT) fluorescent probe for highly selective and sensitive monitoring of H(2)S has been developed. The design takes advantage of the facile reduction of non-fluorescent hydroxyamine naphthalimide by H(2)S to highly fluorescent amine naphthalimide. It has been demonstrated that the probe is able to detect H(2)S at submicromolar concentrations in cells.
一种新型的内电荷转移（ICT）荧光探针，可用于高选择性和高灵敏度监测 H（2）S。该设计利用 H（2）S 将非荧光羟胺萘酰亚胺还原为高荧光胺萘酰亚胺。研究表明，该探针能够在细胞中检测到亚微米浓度的 H（2）S。
