Soft Matter Chemistry, Leiden Institute of Chemistry, P.O. Box 9502, 2300 RA Leiden, The Netherlands.
Angew Chem Int Ed Engl. 2012 Dec 7;51(50):12616-20. doi: 10.1002/anie.201204836. Epub 2012 Sep 26.
Patchy surfaces: An azide-terminated self-assembled monolayer was patterned with the peptide sequence (EIAALEK)(3) by using microcontact printing. This sequence forms stable coiled-coil heterodimers with the complementary peptide (KIAALKE)(3). By introducing this peptide to the surface of phospholipid liposomes and cyclodextrin vesicles, liposomes and vesicles can be immobilized at the patterned surface.
通过微接触印刷，用末端为叠氮化物的自组装单分子层对多肽序列 (EIAALEK)(3) 进行图案化处理。该序列与互补肽 (KIAALKE)(3) 形成稳定的螺旋卷曲杂二聚体。通过将该肽引入到磷脂脂质体和环糊精囊泡的表面，可以将脂质体和囊泡固定在图案化表面。
