Kemper K J, Forsyth B W, McCarthy P L
Department of Pediatrics, University of Washington, Harborview Medical Center, Seattle 98104.
Am J Dis Child. 1990 Feb;144(2):238-41. doi: 10.1001/archpedi.1990.02150260118043.
Treatments for neonatal jaundice are generally considered both safe and effective. We hypothesized that such treatments would be associated with symptoms of the vulnerable child syndrome, persisting up to 6 months. Mothers of otherwise healthy infants who had jaundice and demographically similar infants without jaundice born at Yale-New Haven (Conn) Hospital were surveyed and compared 6 months after discharge from the hospital. By 6 months, the infants with jaundice had significantly more feeding difficulties, eg, they were less likely to be breast-feeding. Unexpectedly, the mothers of infants with jaundice switched from being less likely to leave their infants with someone else at 1 month to leaving the infants significantly more than mothers of infants in the comparison group. Although the mothers of infants in the comparison group reported a similar number of infant health problems, the mothers of infants with jaundice were more likely to judge the problems as serious and to have taken the infant to an emergency department. The benefits of treating jaundice in otherwise healthy infants should be weighted against the risks of developing the vulnerable child syndrome.
新生儿黄疸的治疗通常被认为是安全有效的。我们推测，此类治疗可能会与脆弱儿童综合征的症状相关，且这种症状会持续长达6个月。我们对耶鲁-纽黑文（康涅狄格州）医院出生的患有黄疸的健康婴儿的母亲以及人口统计学特征相似的无黄疸婴儿的母亲进行了调查，并在她们出院6个月后进行了比较。到6个月时，患有黄疸的婴儿出现喂养困难的情况明显更多，例如，他们进行母乳喂养的可能性更低。出乎意料的是，患有黄疸的婴儿的母亲从1个月时不太可能将婴儿交给他人照料，转变为比对照组婴儿的母亲更频繁地将婴儿交给他人照料。尽管对照组婴儿的母亲报告的婴儿健康问题数量相似，但患有黄疸的婴儿的母亲更有可能认为这些问题严重，并带婴儿去过急诊科。对于健康婴儿治疗黄疸的益处，应该与发展为脆弱儿童综合征的风险进行权衡。
