Piccione P R, Holt P R, Culpepper-Morgan J A, Paris P, O'Bryan L, Ferdinands L, Kreek M J
Department of Medicine, St. Luke's Roosevelt Hospital Center, College of Physicians & Surgeons, Columbia University, New York, New York.
Am J Gastroenterol. 1990 Feb;85(2):161-4.
Altered bowel habits are common symptoms in the elderly, yet the pathophysiology of age-related gastrointestinal dysmotility syndromes is poorly understood. The present study was designed to correlate changes in orocecal transit time (TT) in healthy elderly subjects with or without gastrointestinal dysmotility complaints. Twenty-two geriatric facility resident volunteers, mean age 82 yr (range 65-94 yr) participated, of whom 16 had gastrointestinal dysmotility symptoms. Orocecal TT in the elderly subjects did not differ from that in younger adult controls (100 +/- 11 min vs 93 +/- 20 min). However, orocecal TT was longer in geriatric females (112 +/- 14 min) than in males (70 +/- 6 min, p less than 0.01). We conclude that age alone does not prolong orocecal TT, except when dysmotility symptoms have been present for a prolonged period.
肠道习惯改变是老年人常见的症状，但与年龄相关的胃肠动力障碍综合征的病理生理学仍知之甚少。本研究旨在关联有无胃肠动力障碍主诉的健康老年受试者口盲肠转运时间（TT）的变化。22名老年护理机构居民志愿者参与了研究，平均年龄82岁（范围65 - 94岁），其中16人有胃肠动力障碍症状。老年受试者的口盲肠TT与年轻成人对照组无差异（100±11分钟 vs 93±20分钟）。然而，老年女性的口盲肠TT（112±14分钟）比男性（70±6分钟，p<0.01）更长。我们得出结论，仅年龄本身不会延长口盲肠TT，除非动力障碍症状已持续较长时间。
