Rana S V, Sharma S, Sinha S K, Prasad K K, Bhasin D K, Singh K
Department of Gastroentrology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Trop Gastroenterol. 2008 Apr-Jun;29(2):98-100.
The mechanisms responsible for bowel disturbances in celiac disease are still unknown. Small bowel motor abnormalities may be involved in this pathological condition; however, there is no study addressing small bowel transit in patients of celiac disease from Northern India.
The mouth-to-cecum transit time was studied in 80 celiac patients and 80 age and sex matched apparently healthy controls.
Orocecal transit time in celiac patients was significantly delayed being 180+/-10.6 minutes (Mean+/-SE) as compared to 105+/-12.4 minutes in apparently healthy controls.
This prolonged orocecal transit time could be due to impaired small bowel function (deranged motility) in patients with celiac disease.
乳糜泻中肠道功能紊乱的机制仍不清楚。小肠运动异常可能参与了这一病理状况；然而，尚无针对印度北部乳糜泻患者小肠转运的研究。
对80例乳糜泻患者以及80例年龄和性别相匹配的貌似健康的对照者进行了口至盲肠转运时间的研究。
乳糜泻患者的口盲肠转运时间显著延迟，为180±10.6分钟（均值±标准误），而貌似健康的对照者为105±12.4分钟。
这种延长的口盲肠转运时间可能是由于乳糜泻患者小肠功能受损（运动紊乱）所致。
