Laboratoire de Génétique et Physiologie Bactérienne, Institut de Biologie et de Médecine Moléculaires, Faculté des Sciences, Bruxelles, Belgium.
Pediatr Infect Dis J. 2013 Jan;32(1):86-7. doi: 10.1097/INF.0b013e3182755cb7.
Streptococcus pneumoniae serotype 1 presents a high invasiveness index and is seldom isolated from its niche, the nasopharynx. We report an unusual serotype 1 carriage in a healthy pediatric population at the time of the heptavalent pneumococcal vaccine adoption in Belgium. Our sampling period coincides with an epidemic wave of serotype 1 invasive pneumococcal infections. Invasive and colonizing isolates were characterized by both antibiotic resistance profile and multilocus sequence typing and were shown to share the same backbone (ST306 and ST350).
肺炎链球菌 1 型具有较高的侵袭性指数，很少从其栖息地鼻咽部分离出来。我们报告了在比利时 7 价肺炎球菌疫苗接种时，健康儿科人群中出现的不常见 1 型携带情况。我们的采样期恰逢 1 型侵袭性肺炎球菌感染的流行浪潮。侵袭性和定植性分离株的抗生素耐药谱和多位点序列分型特征表明它们具有相同的骨架（ST306 和 ST350）。
