Moawad A H, Lee K S, Fisher D E, Ferguson R, Phillippe M
Department of Obstetrics and Gynecology, University of Chicago, IL 60637.
Am J Obstet Gynecol. 1990 Jan;162(1):15-22. doi: 10.1016/0002-9378(90)90811-k.
This prospective study assesses factors that contribute to perinatal mortality. The study population includes the 1362 perinatal deaths that occurred among 85,402 live births between 1983 and 1987 at hospitals of the University of Chicago Perinatal Network. After peer review of demographic, clinical, and pathologic data, each perinatal death was classified in one of the following categories: (1) the result of congenital malformation incompatible with life, (2) unavoidable, (3) potentially avoidable by patient, by health provider, or by both, or (4) of undetermined responsibility. Of 1362 deaths, 12.3% involved congenital malformations incompatible with life, 56.9% were classified as unavoidable, 28.1% were judged potentially avoidable, and 2.7% due to undetermined causes. Of potentially avoidable deaths, 36% were due to patient factors (primarily noncompliance), 59% to health provider factors, and 15% to combined patient and provider factors. There was a significant reduction in the potentially avoidable cases during the study period. The maximum attainable reduction in perinatal mortality under optimal conditions is calculated. Intervention plans to achieve this goal are discussed.
这项前瞻性研究评估了导致围产期死亡的因素。研究人群包括1983年至1987年期间在芝加哥大学围产期网络医院出生的85402例活产中发生的1362例围产期死亡。在对人口统计学、临床和病理数据进行同行评审后,每例围产期死亡被归类为以下类别之一:(1) 与生命不相容的先天性畸形的结果,(2) 不可避免的,(3) 患者、医疗服务提供者或两者都有可能避免的,或 (4) 责任未确定的。在1362例死亡中,12.3% 涉及与生命不相容的先天性畸形,56.9% 被归类为不可避免的,28.1% 被判定为有可能避免的,2.7% 原因未确定。在有可能避免的死亡中,36% 是由于患者因素(主要是不遵守医嘱),59% 是由于医疗服务提供者因素,15% 是由于患者和提供者的综合因素。在研究期间,有可能避免的病例显著减少。计算了在最佳条件下围产期死亡率可达到的最大降低幅度。讨论了实现这一目标的干预计划。