Haberland U H, Blazek V, Schmitt H J
J Biomed Opt. 1998 Jul;3(3):259-66. doi: 10.1117/1.429889.
A new noninvasive technique that reveals cross sectional images of scattering media is presented. It is based on a continuous wave frequency modulated radar, but uses a tunable laser in the near infrared. As the full width at half maximum resolution of 16 μm is demonstrated with an external cavity laser, the chirp optical coherence tomography becomes an alternative to conventional short coherence tomography with the advantage of a simplified optical setup. The analysis of two-layer solid phantoms shows that the backscattered light gets stronger with decreasing anisotropic factor and increasing scattering coefficient, as predicted by Monte Carlo simulations. By introducing a two-phase chirp sequence, the combination of lateral resolved perfusion and depth resolved structure is shown. © 1998 Society of Photo-Optical Instrumentation Engineers.
本文介绍了一种能够揭示散射介质横截面图像的新型非侵入性技术。该技术基于连续波调频雷达，但使用近红外可调谐激光器。由于外腔激光器展示出了16μm的半高宽分辨率，啁啾光学相干断层扫描成为传统短相干断层扫描的替代方案，具有简化光学设置的优势。对双层固体模型的分析表明，如蒙特卡罗模拟所预测的那样，背向散射光随着各向异性因子的减小和散射系数的增加而变强。通过引入两相啁啾序列，展示了横向分辨灌注和深度分辨结构的结合。©1998 美国光电仪器工程师协会。
