Hata N, Morrison P R, Kettenbach J, Black P M, Kikinis R, Jolesz F A
J Biomed Opt. 1998 Jul;3(3):304-11. doi: 10.1117/1.429857.
Hardware and software for a customized system to use magnetic resonance imaging (MRI) to noninvasively monitor laser-induced interstitial thermal therapy of brain tumors are reported. An open-configuration interventional MRI unit was used to guide optical fiber placement and monitor the deposition of laser energy into the targeted lesion. T1-weighted fast spin echo and gradient echo images were used to monitor the laser tissue interaction. The images were transferred from the MRI scanner to a customized research workstation and were processed intraoperatively. Newly developed software enabled rapid (27-221 ms) availability of calculated images. A case report is given showing images which reveal the laser-tissue interaction. The system design is feasible for on-line monitoring of interstitial laser therapy. © 1998 Society of Photo-Optical Instrumentation Engineers.
本文报道了一种定制系统的硬件和软件，该系统利用磁共振成像（MRI）对脑肿瘤的激光诱导间质热疗进行无创监测。使用开放式配置的介入式MRI设备来引导光纤放置，并监测激光能量在目标病变中的沉积。采用T1加权快速自旋回波和梯度回波图像来监测激光与组织的相互作用。图像从MRI扫描仪传输到定制的研究工作站，并在术中进行处理。新开发的软件能够快速（27 - 221毫秒）提供计算图像。给出了一个病例报告，展示了揭示激光与组织相互作用的图像。该系统设计对于间质激光治疗的在线监测是可行的。© 1998光电仪器工程师协会。
