Roggero Paola, Giannì Maria L, Piemontese Pasqua, Amato Orsola, Agosti Massimo, Mosca Fabio
Neonatal Intensive Care Unit (NICU), Department of Clinical Sciences and Community Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
J Matern Fetal Neonatal Med. 2012 Oct;25 Suppl 3:49-52. doi: 10.3109/14767058.2012.712318.
The optimization of the nutritional management of preterm infants has gained importance due to the increased survival of these vulnerable infants. In fact, the achievement of an adequate growth has been associated with a favourable neurodevelopment outcome. Nevertheless, preterm infants still develop severe nutrient deficiencies during the first few weeks of life so that they are frequently growth restricted upon discharge. In addition, preterm infants have been found to show an increased and aberrant adiposity at term-corrected age. The development of strategies immediately after birth has been found to produce excellent results in terms of growth without having any detrimental effect on body composition at term-corrected age. Continuing to monitor growth and body composition changes in relation to different nutrition interventions is essential as growth pattern and body composition appear to have a long term effect on health outcomes.
由于这些脆弱婴儿存活率的提高,优化早产儿的营养管理变得愈发重要。事实上,实现充足的生长与良好的神经发育结果相关。然而,早产儿在出生后的头几周仍会出现严重的营养缺乏,以至于他们在出院时经常生长受限。此外,研究发现早产儿在足月矫正年龄时肥胖增加且异常。已发现出生后立即制定策略在生长方面能产生极佳效果,且对足月矫正年龄时的身体成分没有任何不利影响。持续监测与不同营养干预相关的生长和身体成分变化至关重要,因为生长模式和身体成分似乎对健康结果有长期影响。