Department of Urology, University Medical Center Utrecht, Utrecht, The Netherlands.
J Urol. 2013 Mar;189(3):1066-70. doi: 10.1016/j.juro.2012.08.258. Epub 2012 Sep 24.
Bladder augmentation by enterocystoplasty or detrusorectomy might prevent renal damage, help achieve dryness and decrease the need for antimuscarinics. We compared the long-term outcomes of enterocystoplasty and detrusorectomy in adults with spina bifida.
A retrospective study using the hospital electronic database was performed. We identified 47 patients with spina bifida (median age at followup 26.8 years) who underwent either enterocystoplasty or detrusorectomy between 1988 and 2004. Median followup was 13.1 years in the detrusorectomy group and 15.3 years in the enterocystoplasty group.
In the detrusorectomy group 4 patients with treatment failure were identified. All 4 patients underwent secondary enterocystoplasty. No reoperation was necessary in the enterocystoplasty group. Preoperative bladder volume was approximately 100 ml higher in the detrusorectomy group (not significant). There was a significantly greater improvement of median bladder volume in the enterocystoplasty group (increase of 300 vs 77.5 ml, p = 0.006). No differences in continence rate, antimuscarinic use or condition of the upper tract were found.
In this series of 47 patients long-term outcomes were good after enterocystoplasty and detrusorectomy, although bladder volume exhibited a greater increase in the enterocystoplasty group. No differences were observed among the other outcomes. If preoperative bladder volume is sufficient, detrusorectomy can be considered before enterocystoplasty is done.
通过肠膀胱扩大术或膀胱切除术进行膀胱扩大可能有助于预防肾功能损害、实现控尿并减少抗毒蕈碱药物的使用。我们比较了肠膀胱扩大术和膀胱切除术治疗成人脊髓脊膜膨出的长期效果。
我们使用医院电子数据库进行了回顾性研究。共纳入 47 例脊髓脊膜膨出患者(随访时的中位年龄为 26.8 岁),这些患者分别于 1988 年至 2004 年间接受了肠膀胱扩大术或膀胱切除术。膀胱切除术组的中位随访时间为 13.1 年,肠膀胱扩大术组为 15.3 年。
在膀胱切除术组中,有 4 例患者治疗失败,这 4 例患者均接受了二次肠膀胱扩大术。肠膀胱扩大术组无一例患者需要再次手术。膀胱切除术组术前膀胱容量比肠膀胱扩大术组高约 100ml(无统计学差异)。肠膀胱扩大术组的中位膀胱容量显著增加(增加了 300ml 对 77.5ml,p=0.006)。两组的控尿率、抗毒蕈碱药物使用情况或上尿路情况无差异。
在本系列 47 例患者中,肠膀胱扩大术和膀胱切除术的长期效果良好,尽管肠膀胱扩大术组的膀胱容量增加更为明显。其他结果无差异。如果术前膀胱容量足够,可在进行肠膀胱扩大术之前考虑行膀胱切除术。