Gioviale Maria Concetta, Bellavia Maurizio, Damiano Giuseppe, Lo Monte Attilio Ignazio
Department of Surgical and Oncological Disciplines, Università degli Studi di Palermo, Viadel Vespro 129, Palermo, Italy.
Ann Transplant. 2012 Jul-Sep;17(3):111-9.
Tertiary hyperparathyroidism is intended as a state of excessive autonomous excretion of parathyroid hormone after longstanding secondary hyperparathyroidism. It is a condition of a severe hyperparathyroidism that persists in the renal recipient despite a successful transplantation. The high levels of parathyroid hormone lead to a worsening of graft function accompanied by systemic symptoms. This article reviews the main aspects related to tertiary hyperparathyroidism from mechanism of pathogenesis to prevention and treatment, suggesting some indications about the best management of patients on a waiting list for kidney transplant.
tertiary 甲状旁腺功能亢进是指在长期继发性甲状旁腺功能亢进后出现的甲状旁腺激素自主分泌过多的状态。它是一种严重的甲状旁腺功能亢进症，尽管肾移植成功，但在肾移植受者中仍然持续存在。高水平的甲状旁腺激素会导致移植肾功能恶化，并伴有全身症状。本文从发病机制到预防和治疗等方面综述了与 tertiary 甲状旁腺功能亢进相关的主要内容，为肾移植等待名单上的患者的最佳管理提供了一些指导意见。
