Great Lakes Bioenergy Research Center, Michigan State University East Lansing, MI, USA ; Plant Research Laboratory, Department of Energy, Michigan State University East Lansing, MI, USA.
Front Plant Sci. 2012 Feb 10;3:28. doi: 10.3389/fpls.2012.00028. eCollection 2012.
Secretory organelles are engaged in a continuous flux of membranes, which is believed to occur mostly via transport vesicles. Being critical in maintaining several cellular functions, transport vesicles are membrane-enclosed sacs that temporarily store and then deliver membrane lipids, protein, and polysaccharides. SNAREs have a crucial role in vesicle traffic by driving membrane fusion and conferring fidelity through the formation of specific SNARE complexes. Additionally, specific roles of SNAREs in growth and development implicate that they are versatile components for the life of a plant. Here, we summarize the recent progress on the understanding of the role of SNAREs and highlight some of the questions that are still unsolved.
分泌细胞器参与膜的持续流动,据信这种流动主要通过运输小泡发生。运输小泡是暂时储存并随后输送膜脂、蛋白质和多糖的膜封闭囊泡,对于维持多种细胞功能至关重要。SNARE 在囊泡运输中起着关键作用,通过驱动膜融合并通过形成特定的 SNARE 复合物来保证保真度。此外,SNARE 在生长和发育中的特定作用表明它们是植物生命的多功能组成部分。在这里,我们总结了对 SNARE 作用的理解的最新进展,并强调了一些仍未解决的问题。