Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea.
Korean J Intern Med. 2012 Sep;27(3):346-9. doi: 10.3904/kjim.2012.27.3.346. Epub 2012 Sep 1.
Granulomatous hypophysitis is a rare pituitary condition that commonly presents with enlargement of the pituitary gland. A 31-year-old woman was admitted to the hospital with a severe headache and bitemporal hemianopsia. Magnetic resonance imaging (MRI) showed an 18 × 10-mm sellar mass with suprasellar extension and compression of the optic chiasm. Interestingly, brain MRI had shown no abnormal finding 4 months previously. On hormonal examination, hypopituitarism with mild hyperprolactinemia was noted. The biopsy revealed granulomatous changes with multinucleated giant cells. We herein report this rare case and discuss the relevant literature.
肉芽肿性垂体炎是一种罕见的垂体疾病，常表现为垂体增大。一名 31 岁女性因剧烈头痛和双颞侧偏盲入院。磁共振成像（MRI）显示 18×10mm 的鞍内肿块伴鞍上扩展，压迫视交叉。有趣的是，4 个月前的脑部 MRI 未见异常。在激素检查中，发现垂体功能减退伴轻度高泌乳素血症。活检显示有多核巨细胞的肉芽肿性改变。我们在此报告这一罕见病例，并讨论相关文献。
