Kamulegeya Adriane, William Buwembo, Rwenyonyi Charles Mugisha
Oral & Maxillofacial Unit, Department of Dentistry, Mulago Hospital, Kampala, Uganda.
J Dent Res Dent Clin Dent Prospects. 2011 Spring;5(2):61-6. doi: 10.5681/joddd.2011.013. Epub 2011 Jun 14.
Irrational prescription of antibiotics by clinicians might lead to drug resistance. Clinicians do prescribe antibiotics for either prophylactic or therapeutic reasons. The decision of when and what to prescribe leaves room for misuse and therefore it is imperative to continuously monitor knowledge and pattern of prescription. The aim of the present study was to determine the knowledge of antibiotic use and the prescription pattern among dental health care practitioners in Uganda.
A structured and pretested questionnaire was sent to 350 dental health care practitioners by post or physical delivery. All the questionnaires were sent with self-addressed and prepaid postage envelopes to enable re-spondents to mail back the filled questionnaires. Chi-squared test was used to test for any significant differences between groups of respondents based on qualitative variables.
The response rate was 40.3% (n=140). Of these 52.9 % were public health dental officers (PHDOs) and 47.1% were dental surgeons. The males constituted 74.3% of the respondents. There were statistically significant differences be-tween dental surgeons and (PHDOs) in knowledge on prophylactic antibiotic use (P = 0.001) and patient influence on pre-scription (P = 0.001). Amoxicillin, in combination with metronidazole, was the most common combination of antibiotics used followed by co-trimoxazole with metronidazole.
The knowledge of dental health care practitioners in antibiotic use in this study was generally low. A combi-nation of amoxicillin with metronidazole was the most commonly prescribed antibiotics subsequent to different dental pro-cedures.
临床医生不合理使用抗生素可能导致耐药性。临床医生出于预防或治疗目的开具抗生素。何时开具以及开具何种药物的决定存在滥用空间,因此持续监测用药知识和处方模式至关重要。本研究的目的是确定乌干达牙科保健从业者对抗生素使用的知识以及处方模式。
通过邮寄或亲自送达的方式向350名牙科保健从业者发送一份结构化且经过预测试的问卷。所有问卷均附有回邮地址和邮资已付的信封,以便受访者将填写好的问卷寄回。采用卡方检验来检验基于定性变量的受访者群体之间的任何显著差异。
回复率为40.3%(n = 140)。其中,52.9%为公共卫生牙科官员(PHDOs),47.1%为牙科外科医生。男性占受访者的74.3%。在预防性抗生素使用知识(P = 0.001)和患者对处方的影响(P = 0.001)方面,牙科外科医生和公共卫生牙科官员(PHDOs)之间存在统计学上的显著差异。阿莫西林与甲硝唑联合使用是最常用的抗生素组合,其次是复方新诺明与甲硝唑。
本研究中牙科保健从业者对抗生素使用的知识普遍较低。在不同牙科手术后,阿莫西林与甲硝唑联合使用是最常开具的抗生素组合。