伴有软脑膜癌病的基底鳞状细胞癌

Basosquamous cell carcinoma with leptomeningeal carcinomatosis.

作者信息

Peña Y M, Bason M M, Grant-Kels J M

机构信息

Department of Neurology University of Connecticut Health Center, Farmington 06032.

出版信息

Arch Dermatol. 1990 Feb;126(2):195-8. doi: 10.1001/archderm.1990.01670260065012.

DOI:10.1001/archderm.1990.01670260065012

PMID:2301957

Abstract

A basal cell carcinoma with prominent focal squamous differentiation of the right nasolabial fold resulted in leptomeningeal carcinomatosis, despite appropriate surgical excision of the primary lesion. The controversy surrounding the origin, diagnosis, and prognosis of a basal cell carcinoma with squamous differentiation is reviewed. Potential routes of metastasis leading to the subsequent leptomeningeal carcinomatosis are discussed.

摘要

一例右鼻唇沟基底细胞癌伴显著局灶性鳞状分化，尽管对原发灶进行了适当的手术切除，但仍导致了软脑膜癌转移。本文综述了围绕伴有鳞状分化的基底细胞癌的起源、诊断和预后的争议。讨论了导致随后软脑膜癌转移的潜在转移途径。