Sreeram N, Wren C
Department of Paediatric Cardiology, Freeman Hospital, Newcastle upon Tyne.
Arch Dis Child. 1990 Jan;65(1):127-9. doi: 10.1136/adc.65.1.127.
All patients with supraventricular tachycardia during the first 12 months of life who presented between 1977 and 1988 were identified by a retrospective survey of records in this hospital and by a questionnaire sent to paediatricians in the Northern region. Twenty two of 29 patients (76%) were in heart failure and seven (24%) had cardiogenic shock. Seven patients (24%) were free of symptoms. All had narrow QRS tachycardia at 215-315 beats/minute (mean (SD) 292 (21)). Initial treatment included digoxin (effective in seven of 14 patients, with overdose in three), verapamil (effective in three of three but fatal in one), cardioversion (effective in all 10 who were treated in this way), iced water applied to the face (effective in all 16 patients on 53 of 59 occasions, 90%). Initial treatment in local hospitals was less effective and associated with more complications than that given in the regional referral centre. Digoxin is often ineffective, return to sinus rhythm is delayed, and overdosing is common. Cardioversion is effective but tachycardia often recurs. Iced water is safe and effective, and should become the treatment of choice for termination of supraventricular tachycardia in neonates and young infants.
通过对本院病历的回顾性调查以及向北部地区儿科医生发放问卷,确定了1977年至1988年间12个月以内出现室上性心动过速的所有患者。29例患者中有22例(76%)出现心力衰竭,7例(24%)出现心源性休克。7例患者(24%)无症状。所有患者均为窄QRS波心动过速,心率为215 - 315次/分钟(平均(标准差)292(21))。初始治疗包括地高辛(14例患者中有7例有效,3例过量)、维拉帕米(3例患者中有3例有效,但1例死亡)、心脏复律(接受此治疗的10例患者均有效)、面部冰敷(59次中有53次对16例患者有效,有效率90%)。当地医院的初始治疗效果较差,且与区域转诊中心相比并发症更多。地高辛通常无效,恢复窦性心律延迟,且过量用药常见。心脏复律有效,但心动过速常复发。面部冰敷安全有效,应成为新生儿和小婴儿室上性心动过速终止治疗的首选方法。