Radford D
Arch Dis Child. 1983 Jun;58(6):465-6. doi: 10.1136/adc.58.6.465.
Two infants with supraventricular tachycardia were given intravenous verapamil and subsequently suffered life threatening bradycardia and hypotension. As there were no predisposing factors, direct drug action is implicated and other reports of the adverse effects of verapamil are noted. Supraventricular tachycardia in neonates and young infants may be safely treated with digoxin and cardioversion, and intravenous verapamil should be avoided.
两名患有室上性心动过速的婴儿接受了静脉注射维拉帕米治疗,随后出现危及生命的心动过缓和低血压。由于不存在诱发因素,推测为药物直接作用,并注意到其他关于维拉帕米不良反应的报告。新生儿和幼儿的室上性心动过速可用地高辛和心脏复律安全治疗,应避免静脉注射维拉帕米。