Mertens R, Seyler L, Lacor P, Denis O
Department of Internal Medicine, Infectious Diseases Unit, UZ Brussel, Belgium.
Acta Clin Belg. 2012 Jul-Aug;67(4):235-40. doi: 10.2143/ACB.67.4.2062665.
Community associated methicillin resistant Staphylococcus aureus (CA-MRSA) is an emergent infectious pathogen that might become an important public-health problem. Indeed, unique strains of S. aureus that combine specific virulence factors with resistance against frequently used antibiotics have been associated with severe community acquired infections in otherwise healthy and often younger people. This is especially the case in the USA, were these strains now represent a major part of staphylococcal infections in the outpatient setting. But, severe infections with CA-MRSA strains have already been reported in Belgium as well. This article summarizes the current knowledge on CA-MRSA as an emergent pathogen and discusses its clinical management.
社区获得性耐甲氧西林金黄色葡萄球菌(CA-MRSA)是一种新出现的传染性病原体,可能会成为一个重要的公共卫生问题。事实上,金黄色葡萄球菌的独特菌株将特定毒力因子与对常用抗生素的耐药性结合在一起,与原本健康且往往较年轻人群中的严重社区获得性感染有关。在美国尤其如此,这些菌株现在是门诊环境中葡萄球菌感染的主要部分。但是,比利时也已报告了CA-MRSA菌株引起的严重感染。本文总结了关于CA-MRSA作为一种新出现病原体的当前知识,并讨论了其临床管理。