Wang Liyan, Tian Yixin, Li Haitao, Wang Li, Lv Xiaojun
College of Chinese Medicinal Material, Jilin Agricultural University, Changchun 130118, China.
Zhongguo Zhong Yao Za Zhi. 2012 Jul;37(13):2030-3.
Based on the effect for replenishing Qi and preventing exhaustion, this essay provides a method to rebuild the quality evaluation system of Panax ginseng. As an independent medical system, the traditional Chinese medicine (TCM) science lacks enough credible evidences to support its theory and thereby wants more relevant studies. Current, it is a misunderstanding for experimental studies on TCM to prove TCM drugs from the angle of western medicine. Therefore, following study modes are recommended to researchers focusing on either the theory of the unique importance of class origin or the theory of the unique importance of techniques. Under the guidance of TCM theories, a new TCM assessment mode, consisting of clinical efficacy, pharmacological effect and effective components, is established in line with clinical application of TCMs. Studies on Chemical fingerprint or active ingredient are made on effective components. In-depth studies are worth to the viewpoint to rebuild the TCM quality reassessment system. On the basis of analysis on ancient herbal literatures and experience in clinical application of TCMs, the author proves the irreplaceable effect of P. ginseng. (pure ginseng decoction) is to replenish Qi and prevent exhaustion. Based on the major effect, a pharmacological model is established in combination with modern clinical efficacy to screen effective components of ginseng herbs and make a quality assessment on safety and efficiency of clinical application of P. ginseng, in order to provide theoretical and experimental basis for cultivation, development and utilization of P. ginseng resources on Changbai mountain.
基于补气固脱功效,本文提出了一种重建人参质量评价体系的方法。中医作为一门独立的医学体系,其科学缺乏足够可信的证据来支持其理论,因此需要更多相关研究。目前,从西医角度证明中药药物的实验研究是一种误解。因此,建议关注道地药材理论或炮制理论的研究人员采用以下研究模式。在中医理论指导下,结合中药临床应用,建立一种由临床疗效、药理作用和有效成分组成的新型中医评价模式。对有效成分进行化学指纹图谱或活性成分研究。重建中药质量再评价体系的观点值得深入研究。在对古代本草文献及中药临床应用经验分析的基础上,作者论证了人参(纯人参汤)补气固脱的不可替代作用。基于主要功效,结合现代临床疗效建立药理模型,筛选人参药材的有效成分,并对人参临床应用的安全性和有效性进行质量评价,为长白山人参资源的培育、开发和利用提供理论和实验依据。