Division of Life Science & Health, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China.
J Ethnopharmacol. 2012 Mar 27;140(2):345-67. doi: 10.1016/j.jep.2012.01.027. Epub 2012 Jan 26.
Traditional Chinese medicine (TCM) formulas have been widely used in China since ancient times to treat certain diseases (e.g., phlegm, dampness and blood stasis). Recently, the effects of these medicines have been increasingly demonstrated to be helpful for hyperlipidemic patients.
This manuscript aims to describe the scientific evidence for the efficacy of TCM and attempts to identify potential TCM formulas for treating hyperlipidemia.
TCM formulas approved by the State Food and Drug Administration of China (SFDA) were sourced from the official SFDA website (http://www.sda.gov.cn/). Human and animal evidence for the hypolipidemic effects of herbs from TCM formulas were reviewed via the Internet (Elsevier, ACS, Wiley Online Library, SpringerLink, PubMed, Web of Science, CNKI, Baidu, and Google) and libraries up to October 31, 2011.
More than 50 TCM formulas have been used to treat hyperlipidemia. These herbs can primarily be grouped into three categories: (1) herbs promoting excretions, generally by reducing food retention, enhancing purgative effects, and promoting diuresis and choleretic effects, e.g., Fructus Crataegi (), Radix Polygoni Multiflori (), Semen Cassiae (), and Radix et Rhizoma Rhei (), Rhizoma alismatis (), and Herba Artemisiae Scopariae (); (2) herbs acting on the cardiovascular system, generally by improving blood circulation based on TCM theories, e.g., Radix Salviae Miltiorrhizae (), Radix Puerariae (), Rhizoma Chuanxiong (), Flos Carthami (), and Folium Nelumbinis (); and (3) herbs that have tonic effects, e.g., Fructus Lycii (), Radix Ginseng (), and Radix Astragali ().
Three basic approaches, including excretory function enhancement, cardiovascular system improvement, and tonic effect reinforcement, are emerging among TCM formulas for the treatment of hyperlipidemia. These approaches may be useful in controlling blood lipid levels, preventing cardiovascular complications, and adjusting bodily functions in hyperlipidemic patients. However, solid evidence of the efficacy of these treatments is required.
自古以来，中药（TCM）配方就在中国被广泛用于治疗某些疾病（例如痰、湿和血瘀）。最近，这些药物的效果越来越被证明对高血脂患者有帮助。
本文旨在描述 TCM 的疗效的科学证据，并试图确定治疗高血脂的潜在 TCM 配方。
从国家食品药品监督管理局（SFDA）官方网站（http://www.sda.gov.cn/）获取获得国家食品药品监督管理局批准的 TCM 配方。通过互联网（Elsevier、ACS、Wiley Online Library、SpringerLink、PubMed、Web of Science、CNKI、百度和谷歌）和图书馆检索截至 2011 年 10 月 31 日，对 TCM 配方的草药降血脂作用的人类和动物证据进行了综述。
有 50 多种 TCM 配方用于治疗高血脂。这些草药主要可分为三类：（1）促进排泄的草药，一般通过减少食物滞留、增强泻下作用、促进利尿和利胆作用，如山楂（）、何首乌（）、决明子（）、大黄（）、泽泻（）、薏苡仁（）和青蒿（）；（2）作用于心血管系统的草药，一般通过基于中医理论改善血液循环，如丹参（）、葛根（）、川芎（）、红花（）、荷叶（）；和（3）具有滋补作用的草药，如枸杞（）、人参（）和黄芪（）。
TCM 配方治疗高血脂症的基本方法包括增强排泄功能、改善心血管系统和增强滋补作用。这些方法可能有助于控制血脂水平、预防心血管并发症并调节高血脂患者的身体功能。但是，需要有这些治疗方法疗效的可靠证据。
