[鼠麴草化学成分的研究]
[Study on the chemical constituents from Gnaphalium hypoleucum].
作者信息
Sun Qun, Lu Ye, Wu Shuang-Qing, Yao Shi, Zhang Jian
机构信息
College of Pharmaceutical Science, Soochow University, Suzhou 215123, China.
出版信息
Zhong Yao Cai. 2012 Apr;35(4):566-8.
OBJECTIVE
To research the chemical constituents from Gnaphalium hypoleucum.
METHODS
Compounds were separated by using silica gel, ODS, Sephadex LH-20 chromatography and their structures were elucidated by means of spectral data analysis.
RESULTS
Ten compounds were isolated and identified as tetracosanoic acid (1), 5-hydroxy-3,6,7,8-tetramethoxyflavone (2), beta-sitosterol (3), 5-hydroxy-3,6,7,8,4'-pentamethoxyflavone (4), 5-hydroxy-3,6, 7,8,3',4'-hexamethoxyflavone (5), apigenin (6), luteolin (7), quercetin (8), luteolin4'-O-beta-D-glucoside (9), quercetin-4'-O-beta-D-glucoside (10).
CONCLUSION
All of these compounds are isolated from this plant for the first time. Compound 5 is isolated from the genus for the first time.
目的
研究淡白香青的化学成分。
方法
采用硅胶、ODS、葡聚糖凝胶LH - 20柱色谱法分离化合物，并通过光谱数据分析阐明其结构。
结果
分离鉴定出10个化合物，分别为二十四烷酸（1）、5 - 羟基 - 3,6,7,8 - 四甲氧基黄酮（2）、β - 谷甾醇（3）、5 - 羟基 - 3,6,7,8,4'- 五甲氧基黄酮（4）、5 - 羟基 - 3,6,7,8,3',4'- 六甲氧基黄酮（5）、芹菜素（6）、木犀草素（7）、槲皮素（8）、木犀草素 - 4'- O - β - D - 葡萄糖苷（9）、槲皮素 - 4'- O - β - D - 葡萄糖苷（10）。
结论
所有这些化合物均首次从该植物中分离得到。化合物5首次从该属植物中分离得到。
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