Zhou Tao, Sun Da-Qing, Wu Peng
Department of Angiopathy, Second Hospital of Shandong University, Jinan.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2012 Jul;32(7):918-21.
To observe the clinical effectiveness of Sanmiao Powder (SP) combined fibrinogenase for injection in treatment of acute deep venous thrombosis (ADVT) of lower limbs.
Eighty patients with ADVT were randomly assigned to two groups according to the disease course (within 7 days or 7-28 days), 40 in each group. Every time phase was also divided into two groups, i. e., one group treated with fibrinogenase for injection alone (Group A and C) and another group treated with fibrinogenase for injection + SP administration (Group B and D) , 20 in each group. The clinical effectiveness was observed after 2-week treatment.
The fibrinogenase for injection + SP administration showed better effects in alleviating the swelling of limbs, relieving pain, and lowering fibrinogen. Better effects were obtained in the group with the disease course less than 7 days.
Better effect on ADVT was obtained by integrative medicine.
观察三妙散联合注射用纤维蛋白原酶治疗下肢急性深静脉血栓形成（ADVT）的临床疗效。
将80例ADVT患者按病程（7天内或7 - 28天）随机分为两组，每组40例。每个病程阶段又分为两组，即一组单纯用注射用纤维蛋白原酶治疗（A组和C组），另一组用注射用纤维蛋白原酶 + 三妙散给药治疗（B组和D组），每组20例。治疗2周后观察临床疗效。
注射用纤维蛋白原酶 + 三妙散给药在减轻肢体肿胀、缓解疼痛及降低纤维蛋白原方面效果更好。病程小于7天的组效果更佳。
中西医结合治疗ADVT效果更佳。
