通过99mTc MDP骨SPECT/CT检测到的 Erdheim-Chester病。

Erdheim-Chester disease detected with 99mTc MDP bone SPECT/CT.

作者信息

Ceulemans G, Keyaerts M, Verbruggen L, Hoorens A, Boulet C, Verdries D, De Maeseneer M, Ilsen B, Everaert H

机构信息

Department of Nuclear Medicine, UZ Brussel, Brussels, Belgium.

出版信息

JBR-BTR. 2012 Jul-Aug;95(4):245-8. doi: 10.5334/jbr-btr.630.

DOI:10.5334/jbr-btr.630

PMID:23019992

Abstract

Erdheim-Chester disease (ECD) is a rare non-Langerhans' cell histiocytosis. Mild but permanent juxta-articular bone pain in mainly knees and ankles is the most frequent associated symptom. Despite the pathognomonic radiographic findings, most cases are still diagnosed by the pathologist.The lesions consist of lipid-storing CD 68 +/CD 1a--non-Langerhans' cell histiocytes, most frequently localized in bone but also involving multiple organ systems in the body. We present a case report in which the diagnosis of ECD was established with 99mTc MDP bone SPECT/CT.

摘要

Erdheim-Chester病（ECD）是一种罕见的非朗格汉斯细胞组织细胞增多症。主要累及膝关节和踝关节的轻度但持续性关节周围骨痛是最常见的相关症状。尽管有特征性的影像学表现，但大多数病例仍由病理学家诊断。病变由储存脂质的CD 68 +/CD 1a-非朗格汉斯细胞组织细胞构成，最常累及骨骼，但也可累及身体的多个器官系统。我们报告一例通过99mTc MDP骨SPECT/CT确诊ECD的病例。