超声引导下活检对“干性”间皮瘤的分析。
Analysis of "dry" mesothelioma with ultrasound guided biopsies.
机构信息
Department of Pulmonology, Isala Klinieken, Zwolle, The Netherlands.
出版信息
Lung Cancer. 2012 Dec;78(3):229-33. doi: 10.1016/j.lungcan.2012.09.004. Epub 2012 Sep 26.
BACKGROUND
Image-guided sampling of the thickened pleura is a sensitive approach in patients with malignant pleural mesothelioma with pleural effusion. Malignant pleural mesothelioma presenting without effusion however is more of a diagnostic challenge. In this study we report the diagnostic yield and complications of ultrasound-guided cutting needle biopsies in this particular category of patients.
METHODS
A retrospective database analysis from September 2007 until January 2012 was performed in 56 patients with malignant pleural mesothelioma. Clinical characteristics and results of diagnostic evaluations were analysed.
RESULTS
Of the 56 patients with malignant pleural mesothelioma, 20 patients presented without pleural effusion of with locular effusion. Ultrasound-guided cutting needle biopsy was performed in 14/20 patients with a diagnostic accuracy of 80%. Only 1 patient had mild haemoptysis immediately following biopsies.
CONCLUSION
Diagnosing patients with pleural thickenings suspect for malignant mesothelioma without pleural effusion or with loculated pleural effusion is effective and safe with ultrasound-guided cutting needle biopsies.
背景
在伴有胸腔积液的恶性胸膜间皮瘤患者中，经皮超声引导下胸膜增厚部位取样是一种敏感的方法。然而，对于不伴有胸腔积液的恶性胸膜间皮瘤，诊断更具挑战性。在本研究中，我们报告了超声引导下切割针活检在这一特殊患者群体中的诊断率和并发症。
方法
对 2007 年 9 月至 2012 年 1 月的 56 例恶性胸膜间皮瘤患者进行回顾性数据库分析。分析了患者的临床特征和诊断评估结果。
结果
在 56 例恶性胸膜间皮瘤患者中，20 例患者无胸腔积液或存在分隔性胸腔积液。对 14/20 例患者进行了超声引导下切割针活检，诊断准确率为 80%。仅 1 例患者在活检后立即出现轻度咯血。
结论
超声引导下切割针活检对诊断无胸腔积液或存在分隔性胸腔积液的胸膜增厚疑似恶性间皮瘤患者是有效且安全的。
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