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Serum concentrations of prilocaine following retrobulbar block.

作者信息

Goggin M, Crowley K, O'Malley K, Barry P, Kelly G, Blake J

机构信息

Department of Ophthalmology, St Vincent's Hospital, Dublin.

出版信息

Br J Anaesth. 1990 Jan;64(1):107-9. doi: 10.1093/bja/64.1.107.

DOI:10.1093/bja/64.1.107
PMID:2302367
Abstract

Retrobulbar block for eye surgery is associated with adverse reactions. We performed retrobulbar block in 10 patients using prilocaine (Citanest) and found mean (SD) peak serum concentrations of 851 (165.6) ng ml-1 (range 540-1100 mg ml-1). Peak serum concentrations occurred 3-7 min after the end of administration of the block, and in all cases were less than those associated with toxicity.

摘要

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