School of Medicine, Wayne State University, Detroit, MI 48201, USA.
Psychosom Med. 2012 Oct;74(8):824-31. doi: 10.1097/PSY.0b013e31826bf1ec. Epub 2012 Sep 28.
To determine whether obstructive sleep apnea mediates the relationship between posttraumatic stress disorder (PTSD) and psychosomatic and somatic disorders and its implications for self-rated health (SRH) among Iraqi immigrants in the United States.
A random sample of immigrants who had left Iraq before the 1991 Gulf War (n = 145) or after (n = 205) and are residing in metropolitan Detroit responded to a structured interview covering questions on sociodemographics, premigration trauma, SRH, physician-diagnosed and -treated obstructive sleep apnea, somatic disorders, and psychosomatic disorders. Structural equation modeling was used to evaluate the relationship between premigration trauma scores and health, as well as to explore mediating pathways between PTSD, obstructive sleep apnea, and health.
The prevalence of obstructive sleep apnea among post-Gulf Warimmigrants (30.2%) was significantly higher than among pre-Gulf War immigrants (0.7%; p < .001). Premigration trauma scores were positively associated with depression and PTSD. Structural equation modeling supported a model in which obstructive sleep apnea mediated the relationship between PTSD and psychosomatic and somatic disorders. Premigration trauma also related directly to SRH.
Part of the PTSD-associated adverse health effects observed in Iraqi immigrants is mediated by obstructive sleep apnea. Because sleep apnea in the current study is based on medical history and current treatment, there is a need for future confirmatory polysomnographic studies.
确定阻塞性睡眠呼吸暂停是否在创伤后应激障碍(PTSD)与心身和躯体障碍之间的关系中起中介作用,以及其对居住在美国的伊拉克移民自评健康(SRH)的影响。
从居住在底特律大都市区的曾于海湾战争前(n=145)或之后(n=205)离开伊拉克的移民中随机抽取样本,对其进行了一项结构式访谈,内容涵盖社会人口统计学、前迁移创伤、SRH、经医生诊断和治疗的阻塞性睡眠呼吸暂停、躯体障碍和心身障碍。采用结构方程模型评估了前迁移创伤评分与健康之间的关系,并探讨了 PTSD、阻塞性睡眠呼吸暂停和健康之间的中介途径。
海湾战争后移民中阻塞性睡眠呼吸暂停的患病率(30.2%)明显高于海湾战争前移民(0.7%;p<.001)。前迁移创伤评分与抑郁和 PTSD 呈正相关。结构方程模型支持这样一种模型,即阻塞性睡眠呼吸暂停中介了 PTSD 与心身和躯体障碍之间的关系。前迁移创伤也与 SRH 直接相关。
在伊拉克移民中观察到的部分 PTSD 相关不良健康影响是由阻塞性睡眠呼吸暂停介导的。由于本研究中的睡眠呼吸暂停基于病史和当前治疗,因此需要进行未来的确认性多导睡眠图研究。