Nakai M, Tamaki K, Yamamoto J, Shimouchi A, Maeda M
National Cardiovascular Center Research Institute, Osaka, Japan.
Brain Res. 1990 Jan 15;507(1):168-71. doi: 10.1016/0006-8993(90)90540-r.
To observe the rat brain blood flow with microspheres, a left ventricular catheter for sphere introduction was threaded into position via the right brachial artery. Cross-circulation with a donor rat was employed to prevent any mismatch between the infused and sampled blood volumes. Multiple measurements yielded stable flow data, and the responsiveness to hypercapnia was well preserved, irrespective of the dose of injected spheres (48 x 10(3) and 130 x 10(3)).
为了用微球观察大鼠脑血流量，经右肱动脉将用于引入微球的左心室导管插入到位。采用与供体大鼠的交叉循环来防止注入血量和采样血量之间的任何不匹配。多次测量产生了稳定的血流数据，并且无论注入微球的剂量（48×10³和130×10³）如何，对高碳酸血症的反应性都得到了很好的保留。
