Service de Neurologie, Hôpital Lariboisière, APHP, Université Paris-Diderot, France.
Thromb Res. 2012 Oct;130 Suppl 1:S19-22. doi: 10.1016/j.thromres.2012.08.264.
Cerebral venous thrombosis (CVT) is a rare variety of cerebro-vascular disease accounting for 0.5% of all stroke. It can occur at any age. It has a 3/1 female preponderance with a peak in young women due to gender specific risk factors, especially oral contraceptives and to lesser extent pregnancy, post-partum, and in vitro fertilization. Despite a wide variety of clinical presentations, early diagnosis, mostly based on MRI/MRA, is crucial but often difficult particularly during post-partum because of the numerous causes of headache that may occur after delivery. Antithrombotic treatment based on low molecular weight heparin and symptomatic treatment should be started as rapidly as possible. The overall prognosis of CVT is much better than that of arterial stroke and it is even better in women with gender specific risk factors, with a complete recovery in 80% of patients. Future pregnancy is not contra-indicated, but contraception with oestro-progestogens is definitely contra-indicated.
脑静脉血栓形成（CVT）是一种罕见的脑血管疾病，占所有中风的 0.5%。它可以发生在任何年龄。由于特定于性别的风险因素，尤其是口服避孕药，其次是妊娠、产后和体外受精，女性发病率是男性的 3 倍，优势比为 1/3。尽管有多种临床表现，但早期诊断（主要基于 MRI/MRA）至关重要，但由于分娩后可能出现许多头痛的原因，早期诊断通常很困难。应尽快开始基于低分子肝素的抗血栓治疗和对症治疗。CVT 的总体预后明显优于动脉性中风，对于具有特定于性别的风险因素的女性，预后更好，80%的患者完全恢复。未来妊娠并非禁忌，但肯定禁用雌激素-孕激素避孕药。
