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机器人辅助远端胃切除术后的手术应激及其经济影响。

Surgical stress after robot-assisted distal gastrectomy and its economic implications.

机构信息

Gastric Cancer Branch, National Cancer Centre, Goyang-si, Gyeonggi-do, Korea.

出版信息

Br J Surg. 2012 Nov;99(11):1554-61. doi: 10.1002/bjs.8887.

Abstract

BACKGROUND

There is a lack of reports evaluating the outcomes of robotic gastrectomy and conventional laparoscopic surgery. The aim of this study was to compare the surgical stress response and costs of robot-assisted distal gastrectomy (RADG) with those of laparoscopy-assisted distal gastrectomy (LADG).

METHODS

This prospective study compared a cohort of patients who had RADG with a cohort that underwent conventional LADG for early gastric cancer between March 2010 and May 2011. The surgical outcomes including Eastern Cooperative Oncology Group performance status and complications, surgical stress response and overall costs were compared between the two groups.

RESULTS

Thirty patients were enrolled in the RADG group and 120 in the LADG group. There were no conversions. Median duration of operation was longer in the RADG group (218 (interquartile range 200-254) versus 140 (118-175) min; P < 0·001). Postoperative abdominal drain production was less (P = 0·001) and postoperative performance status was worse (P < 0·001) in the RADG group. C-reactive protein (CRP) levels on postoperative days 1 and 3, and interleukin (IL) 6 level on the third postoperative day, were lower in the LADG compared with the RADG group (CRP: P = 0·002 and P = 0·014 respectively; IL-6: P < 0·001). Costs for robotic surgery were much higher than for laparoscopic surgery (difference €3189).

CONCLUSION

RADG did not reduce surgical stress compared with LADG. The substantial RADG costs due to robotic system expenses may not be justified.

摘要

背景

目前缺乏关于机器人胃切除术和传统腹腔镜手术结果的评估报告。本研究旨在比较机器人辅助远端胃切除术(RADG)与腹腔镜辅助远端胃切除术(LADG)的手术应激反应和成本。

方法

本前瞻性研究比较了 2010 年 3 月至 2011 年 5 月期间接受 RADG 和常规 LADG 治疗早期胃癌的两组患者。比较两组患者的手术结果(包括东部肿瘤协作组体力状态和并发症)、手术应激反应和总费用。

结果

RADG 组纳入 30 例患者,LADG 组纳入 120 例患者。两组均无中转开腹。RADG 组手术时间中位数较长(218(四分位距 200-254)比 140(118-175)min;P<0·001)。RADG 组术后腹部引流物生成量较少(P=0·001),术后体力状态更差(P<0·001)。与 RADG 组相比,LADG 组术后第 1、3 天 C 反应蛋白(CRP)水平和术后第 3 天白细胞介素(IL)6 水平较低(CRP:P=0·002 和 P=0·014;IL-6:P<0·001)。机器人手术的费用明显高于腹腔镜手术(差值 3189 欧元)。

结论

与 LADG 相比,RADG 并未减轻手术应激。由于机器人系统费用较高,RADG 的大量成本可能不合理。

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