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一名遗传性癫痫患者三相波与癫痫放电的比较。

Comparison of triphasic waves and epileptic discharges in one patient with genetic epilepsy.

机构信息

Johns Hopkins University School of Medicine, Baltimore, MD, USA.

出版信息

J Clin Neurophysiol. 2012 Oct;29(5):458-61. doi: 10.1097/WNP.0b013e31826bde70.

Abstract

Genetic epilepsies with generalized spike-wave complexes (GSWCs) and encephalopathy triphasic waves (TWs) may resemble each other and have three phases per complex. Electroencephalographic (EEG) interpretation is subjective, and EEGers have noted "TWs" in cases labeled nonconvulsive status epilepticus (NCSE). Direct comparison of both wave forms under the same conditions is rarely possible. In a single patient with generalized spike waves who developed hepatic TWs, morphologic characteristics of both were compared, and it was found that GSWCs have higher frequency first, second, and third phases; steeper phase 2 slope; and briefer after-going slow waves maximal at F3 to F4. Total complex duration was approximately 0.12 seconds. The TWs had dominant high-voltage phases 2 and 3 located more posteriorly, in the frontocentral region, lasting an average of approximately 0.32 seconds. These morphologic distinctions may help differentiate TWs from GSWCs.

摘要

具有广义棘慢波复合波(GSWCs)和三相波(TWs)的遗传性癫痫可能彼此相似,每个复合波有三个相。脑电图(EEG)的解释是主观的,脑电图医师注意到在被标记为非惊厥性癫痫持续状态(NCSE)的病例中存在“TWs”。在相同条件下对两种波形式进行直接比较很少见。在一个出现肝性 TWs 的全身性棘慢波患者中,比较了两种波的形态特征,发现 GSWCs 的第一、第二和第三相频率更高;相位 2 斜率更陡;随后的慢波在 F3 至 F4 最大,持续时间更短。总复合波持续时间约为 0.12 秒。TWs 的高电压相 2 和 3 主要位于后部,在前中央区域,平均持续时间约为 0.32 秒。这些形态学差异可能有助于将 TWs 与 GSWCs 区分开来。

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