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遗传性全面性癫痫。

Genetic generalized epilepsies.

机构信息

Division of Pediatric Neurology, Duke University Medical Center, Durham, NC, USA.

出版信息

J Clin Neurophysiol. 2012 Oct;29(5):408-19. doi: 10.1097/WNP.0b013e31826bd92a.

Abstract

In the International League Against Epilepsy's most recent revision of classification and terminology, the term idiopathic epilepsy, previously used to describe those epilepsies whose cause was unknown, but presumed genetic, has been removed. It has been replaced by the term genetic epilepsy, only to be used to describe epilepsy in which the etiology has a known or presumed genetic defect in which seizures are the core symptom of the disorder. The purpose of this article was to review the electroclinical spectrum of those epilepsies that would fall under this new designation of genetic epilepsies in the context of specific generalized epilepsy syndromes providing an update in the clinical, electroencephalographic, and genetic findings in these syndromes.

摘要

在国际抗癫痫联盟最近修订的分类和术语中,先前用于描述那些病因不明但推测为遗传性的癫痫的术语“特发性癫痫”已被删除。它已被“遗传性癫痫”所取代,仅用于描述病因已知或推测为遗传缺陷的癫痫,其中癫痫发作是该疾病的核心症状。本文的目的是在特定的全面性癫痫综合征的背景下,回顾那些符合遗传性癫痫这一新定义的癫痫的电临床谱,提供这些综合征的临床、脑电图和遗传发现的最新信息。

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