持久性接触性荨麻疹。蓖麻子引起的I型和IV型过敏以及系统性IgE介导的过敏性皮炎假说。
Long-lasting contact urticaria. Type I and type IV allergy from castor bean and a hypothesis of systemic IgE-mediated allergic dermatitis.
作者信息
Kanerva L, Estlander T, Jolanki R
机构信息
Division of Occupational Dermatology, National Institute of Occupational Health, Solna, Sweden.
出版信息
Dermatol Clin. 1990 Jan;8(1):181-8.
PMID:2302858
Abstract
A unique urticarial type I patch-test reaction to castor bean that persisted for more than 48 hours and was followed by a delayed type IV reaction is described. Immunohistochemical and electron microscopic observations indicated involvement of eosinophils and IgE receptors on Langerhans' cells. The authors present a scheme for the role of Langerhans' cells in skin allergy.
摘要
本文描述了一种对蓖麻籽独特的I型斑贴试验荨麻疹反应，该反应持续超过48小时，并随后出现迟发型IV型反应。免疫组织化学和电子显微镜观察表明，嗜酸性粒细胞和朗格汉斯细胞上的IgE受体参与其中。作者提出了朗格汉斯细胞在皮肤过敏中作用的机制。
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