Bruynzeel D P, Prevoo R L
Department of Occupational Dermatology, Free University Academic Hospital, Amsterdam, The Netherlands.
Dermatol Clin. 1990 Jan;8(1):85-7.
Experience is necessary to use commercially available spices and seasonings for patch testing. This experience is easily obtained by composing your own series of locally important flavorings and by using this series to assess the irritant potency. In our patients, not many strong irritation reactions were elicited. Only 100 per cent garlic powder was obviously too irritant, whereas 25 per cent in petrolatum might be too low to detect allergy. Positive reactions to unknown spices need to be checked in controls; this is important when patch tests are done with spices brought in by the patient. A positive patch-test reaction to a fragrance or perfume indicator in housewives, cooks, and confectioners with hand eczema is an indication to perform patch tests with spices because of the relation between spices and fragrances.
使用市售香料和调味料进行斑贴试验需要经验。通过自行配制一系列当地常用的调味品，并使用该系列来评估刺激强度，很容易获得这种经验。在我们的患者中，引发的强烈刺激反应并不多。只有100%的大蒜粉刺激性明显过大，而凡士林基质中25%的大蒜粉可能浓度过低，无法检测出过敏反应。对未知香料的阳性反应需要在对照中进行检查；当用患者自带的香料进行斑贴试验时，这一点很重要。家庭主妇、厨师和患有手部湿疹的糖果师对香料或香水指示剂的斑贴试验呈阳性反应，由于香料和香水之间的关系，这表明需要对香料进行斑贴试验。
