University Hospital of Giessen & Marburg, Marburg Site, Germany.
Future Oncol. 2012 Sep;8(9):1135-47. doi: 10.2217/fon.12.112.
Advanced epithelial ovarian cancer, cancer of the fallopian tube and primary peritoneal cancer have a poor prognosis and a high rate of disease recurrence following primary therapy. Recurrent ovarian cancer is currently classified according to sensitivity to platinum-based chemotherapy. Data on targeted therapy provide evidence of improvement with systemic treatment in addition to chemotherapy. Other strategies, although not proven in randomized trials, offer interesting options for future research and therapeutic development. In this review, the covered treatment modalities include surgery, chemotherapy and targeted therapy, immunological approaches and irradiation.
高级别上皮性卵巢癌、输卵管癌和原发性腹膜癌的预后较差，且在初始治疗后疾病复发率较高。复发性卵巢癌目前根据对铂类化疗的敏感性进行分类。靶向治疗数据提供了除化疗以外的全身性治疗改善的证据。其他策略虽然没有在随机试验中得到证实，但为未来的研究和治疗发展提供了有趣的选择。在这篇综述中，涵盖的治疗方式包括手术、化疗和靶向治疗、免疫方法和放疗。
