Ruiz Beguerie Julieta, Fernandez Penas Pablo, Sharma Raghwa
Department of Dermatology, Westmead Hospital, Westmead, New South Wales, Australia.
Dermatol Online J. 2012 Sep 15;18(9):8.
We report the case of a 45-year-old female patient previously diagnosed with subacute cutaneous lupus erythematosus who presented with a one-week history of fever, tender erythematous nodules on her limbs, and palpable lymphadenopathy. Two incisional biopsies showed histiocytic infiltrates with abundant nuclear debris in the dermis and at the dermosubcutaneous junction with absence of neutrophils, characteristic of Kikuchi-Fujimoto disease (KFD). The dermatologic and dermopathologic details of KFD are very heterogeneous and yet poorly described. We have reviewed the literature regarding KFD cases reported with cutaneous involvement trying to assess the skin features of the KFD or histiocytic necrotizing lymphadenitis.
我们报告了一例45岁女性患者，该患者先前被诊断为亚急性皮肤型红斑狼疮，此次出现发热一周、四肢有压痛性红斑结节以及可触及的淋巴结病。两次切开活检显示真皮层和真皮皮下交界处有组织细胞浸润，伴有大量核碎片，无中性粒细胞，这是菊池-藤本病（KFD）的特征。KFD的皮肤和皮肤病理学细节非常多样，但描述甚少。我们回顾了有关报道有皮肤受累的KFD病例的文献，试图评估KFD或组织细胞坏死性淋巴结炎的皮肤特征。
