Cramer Jp, Schmiedel S, Alegre N G, Schäfer H, Burchard G D, Merz H
Section for Tropical Medicine, I, Department of Internal Medicine, University Medical Centre Hamburg-Eppendorf, Bernhard-Nocht-Strasse 74, 20359 Hamburg, Germany.
Lupus. 2010 Jan;19(1):89-92. doi: 10.1177/0961203309345793. Epub 2009 Nov 23.
Differentiation between lymphadenopathy in potentially life-threatening systemic lupus erythematosus (SLE) and self-limiting necrotizing lymphadenitis, also called Kikuchi- Fujimoto disease (KFD), is difficult. In the past, co-occurrence of SLE and KFD has been described repeatedly in case reports. Here, we report a case of necrotizing lymphadenitis, describe the clinical and histopathologic features in detail and discuss the current literature. KFD may in fact be a histopathologic characteristic of SLE supporting the hypothesis that KFD is a rare manifestation of SLE. To clarify whether KFD is the same entity as lupus lymphadenitis, more cases with SLE and lymphadenopathy should be examined in detail.
区分潜在危及生命的系统性红斑狼疮（SLE）中的淋巴结病与自限性坏死性淋巴结炎（也称为菊池-藤本病，KFD）很困难。过去，病例报告中曾多次描述过SLE和KFD的共存情况。在此，我们报告一例坏死性淋巴结炎病例，详细描述其临床和组织病理学特征，并讨论当前文献。事实上，KFD可能是SLE的一种组织病理学特征，支持KFD是SLE罕见表现的假说。为了阐明KFD是否与狼疮性淋巴结炎为同一实体，应更详细地检查更多SLE和淋巴结病病例。
