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New functions for ecotropic viral integration site 1 (EVI1), an oncogene causing aggressive malignant disease.

作者信息

Wieser Rotraud

机构信息

Department of Medicine I and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

出版信息

Cell Cycle. 2012 Nov 1;11(21):3915. doi: 10.4161/cc.22392. Epub 2012 Oct 3.

DOI:10.4161/cc.22392
PMID:23032258
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3507483/
Abstract
摘要

相似文献

1
New functions for ecotropic viral integration site 1 (EVI1), an oncogene causing aggressive malignant disease.嗜亲性病毒整合位点1（EVI1）的新功能，EVI1是一种可引发侵袭性恶性疾病的致癌基因。
Cell Cycle. 2012 Nov 1;11(21):3915. doi: 10.4161/cc.22392. Epub 2012 Oct 3.
2
Overexpression of EVI1 interferes with cytokinesis and leads to accumulation of cells with supernumerary centrosomes in G0/1 phase.EVI1 的过表达干扰胞质分裂，导致 G0/G1 期具有过多中心体的细胞积累。
Cell Cycle. 2012 Sep 15;11(18):3492-503. doi: 10.4161/cc.21801. Epub 2012 Aug 16.
3
EVI1 targets ΔNp63 and upregulates the cyclin dependent kinase inhibitor p21 independent of p53 to delay cell cycle progression and cell proliferation in colon cancer cells.EVI1 靶向 ΔNp63 并上调细胞周期蛋白依赖性激酶抑制剂 p21，而不依赖于 p53，以延缓结肠癌细胞的细胞周期进程和增殖。
Int J Biochem Cell Biol. 2013 Aug;45(8):1568-76. doi: 10.1016/j.biocel.2013.04.032. Epub 2013 May 9.
4
Physical and functional interaction of the proto-oncogene EVI1 and tumor suppressor gene HIC1 deregulates Bcl-xL mediated block in apoptosis.
Int J Biochem Cell Biol. 2014 Aug;53:320-8. doi: 10.1016/j.biocel.2014.05.037. Epub 2014 Jun 5.
5
Maintenance of the hematopoietic stem cell pool in bone marrow niches by EVI1-regulated GPR56.EVI1 调控的 GPR56 维持骨髓龛中的造血干细胞池。
Leukemia. 2013 Aug;27(8):1637-49. doi: 10.1038/leu.2013.75. Epub 2013 Mar 12.
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Ecotropic viral integration site 1, a novel oncogene in prostate cancer.嗜亲性病毒整合位点1，前列腺癌中的一种新型致癌基因。
Oncogene. 2017 Mar;36(11):1573-1584. doi: 10.1038/onc.2016.325. Epub 2016 Sep 12.
7
Ecotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer and is a synergistic partner for FOS protein in invasive tumors.异位病毒整合位点 1（EVI1）调节癌症相关的多种重要细胞过程，是侵袭性肿瘤中 FOS 蛋白的协同伙伴。
Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):2168-73. doi: 10.1073/pnas.1119229109. Epub 2012 Jan 19.
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A novel interaction between the proto-oncogene Evi1 and histone methyltransferases, SUV39H1 and G9a.原癌基因Evi1与组蛋白甲基转移酶SUV39H1和G9a之间的新型相互作用。
FEBS Lett. 2008 Aug 6;582(18):2761-7. doi: 10.1016/j.febslet.2008.06.056. Epub 2008 Jul 11.
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Angiopoietin1 contributes to the maintenance of cell quiescence in EVI1(high) leukemia cells.血管生成素 1 有助于 EVI1(high) 白血病细胞的静止状态维持。
Biochem Biophys Res Commun. 2011 Dec 16;416(3-4):239-45. doi: 10.1016/j.bbrc.2011.10.061. Epub 2011 Oct 18.
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Functional features of EVI1 and EVI1Δ324 isoforms of MECOM gene in genome-wide transcription regulation and oncogenicity.MECOM 基因的 EVI1 和 EVI1Δ324 异构体在全基因组转录调控和致癌性中的功能特征。
Oncogene. 2016 May 5;35(18):2311-21. doi: 10.1038/onc.2015.286. Epub 2015 Aug 3.

引用本文的文献

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EVI1 in Leukemia and Solid Tumors.白血病和实体瘤中的EVI1
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2
Disease-stabilizing treatment based on all-trans retinoic acid and valproic acid in acute myeloid leukemia - identification of responders by gene expression profiling of pretreatment leukemic cells.基于全反式维甲酸和丙戊酸的急性髓系白血病的疾病稳定治疗 - 通过预处理白血病细胞的基因表达谱鉴定应答者。
BMC Cancer. 2017 Sep 6;17(1):630. doi: 10.1186/s12885-017-3620-y.
3
Correlations of common polymorphism of EVI-1 gene targeted by miRNA-206/133b with the pathogenesis of breast cancer.miRNA-206/133b靶向的EVI-1基因常见多态性与乳腺癌发病机制的相关性
Tumour Biol. 2014 Sep;35(9):9255-62. doi: 10.1007/s13277-014-2213-5. Epub 2014 Jun 17.
4
EVI1 inhibits apoptosis induced by antileukemic drugs via upregulation of CDKN1A/p21/WAF in human myeloid cells.EVI1 通过上调人髓细胞中的 CDKN1A/p21/WAF 抑制抗白血病药物诱导的细胞凋亡。
PLoS One. 2013;8(2):e56308. doi: 10.1371/journal.pone.0056308. Epub 2013 Feb 14.

本文引用的文献

1
Overexpression of EVI1 interferes with cytokinesis and leads to accumulation of cells with supernumerary centrosomes in G0/1 phase.EVI1 的过表达干扰胞质分裂，导致 G0/G1 期具有过多中心体的细胞积累。
Cell Cycle. 2012 Sep 15;11(18):3492-503. doi: 10.4161/cc.21801. Epub 2012 Aug 16.
2
Clinical, molecular, and prognostic significance of WHO type inv(3)(q21q26.2)/t(3;3)(q21;q26.2) and various other 3q abnormalities in acute myeloid leukemia.急性髓系白血病中 WHO 类型 inv(3)(q21q26.2)/t(3;3)(q21;q26.2) 和其他各种 3q 异常的临床、分子和预后意义。
J Clin Oncol. 2010 Aug 20;28(24):3890-8. doi: 10.1200/JCO.2010.29.2771. Epub 2010 Jul 26.
3
Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease.基因治疗慢性肉芽肿病后 EVI1 激活导致基因组不稳定和 7 号单体性骨髓增生异常。
Nat Med. 2010 Feb;16(2):198-204. doi: 10.1038/nm.2088. Epub 2010 Jan 24.
4
Genetic instabilities in human cancers.人类癌症中的基因不稳定性。
Nature. 1998 Dec 17;396(6712):643-9. doi: 10.1038/25292.
5
Retroviral activation of a novel gene encoding a zinc finger protein in IL-3-dependent myeloid leukemia cell lines.在依赖白细胞介素-3的髓系白血病细胞系中，一种编码锌指蛋白的新基因的逆转录病毒激活。
Cell. 1988 Sep 9;54(6):831-40. doi: 10.1016/s0092-8674(88)91175-0.
6
Activation of EVI1 gene expression in human acute myelogenous leukemias by translocations spanning 300-400 kilobases on chromosome band 3q26.3号染色体3q26带跨度300 - 400千碱基的易位激活人类急性髓性白血病中EVI1基因的表达。
Proc Natl Acad Sci U S A. 1992 May 1;89(9):3937-41. doi: 10.1073/pnas.89.9.3937.
7
Evi-1 expression in leukemic patients with rearrangements of the 3q25-q28 chromosomal region.
Leukemia. 1992 Feb;6(2):93-9.