Font J, Herrero C, Bosch X, Cervera R, Ingelmo M, Mascaró J M
Service of Internal Medicine, Hospital Clinic i Provincial, Barcelona, Spain.
J Am Acad Dermatol. 1990 Feb;22(2 Pt 2):337-40. doi: 10.1016/0190-9622(90)70042-g.
Systemic lupus erythematosus developed in a 35-year-old woman who had partial lipodystrophy since she was 7 years old. To our knowledge, this association has been reported only once. She also had hypocomplementemia, mesangiocapillary glomerulonephritis type II, and a serum assay with positive results for C3 nephritic factor. The association of partial lipodystrophy with other autoimmune disorders suggests an immunologic pathogenesis for this disease.
一名35岁女性自7岁起出现部分性脂肪营养不良，后患上系统性红斑狼疮。据我们所知，这种关联仅被报道过一次。她还存在低补体血症、II型系膜毛细血管性肾小球肾炎，以及C3肾炎因子血清检测呈阳性。部分性脂肪营养不良与其他自身免疫性疾病的关联提示了该疾病的免疫发病机制。
