Polyclonal immunoglobulin free light chain and chronic inflammation.
作者信息
Redegeld Frank A, Thio Marco, Groot Kormelink Tom
出版信息
Mayo Clin Proc. 2012 Oct;87(10):1032-3; author reply 1033. doi: 10.1016/j.mayocp.2012.07.012.
Abstract
摘要
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本文引用的文献
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Mayo Clin Proc. 2012 Jun;87(6):517-23. doi: 10.1016/j.mayocp.2012.03.009.
2
Using single protein biomarkers to predict health and disease in diverse patient populations: a new role for assessment of immunoglobulin free light chains.使用单一蛋白质生物标志物预测不同患者群体的健康与疾病：免疫球蛋白游离轻链评估的新作用。
Mayo Clin Proc. 2012 Jun;87(6):505-7. doi: 10.1016/j.mayocp.2012.04.004.
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An association between neutrophils and immunoglobulin free light chains in the pathogenesis of chronic obstructive pulmonary disease.中性粒细胞与免疫球蛋白游离轻链在慢性阻塞性肺疾病发病机制中的关联。
Am J Respir Crit Care Med. 2012 Apr 15;185(8):817-24. doi: 10.1164/rccm.201104-0761OC. Epub 2012 Jan 6.
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Immunoglobulin free light chains are increased in hypersensitivity pneumonitis and idiopathic pulmonary fibrosis.免疫球蛋白游离轻链在过敏性肺炎和特发性肺纤维化中增加。
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Decrease in immunoglobulin free light chains in patients with rheumatoid arthritis upon rituximab (anti-CD20) treatment correlates with decrease in disease activity.类风湿关节炎患者在利妥昔单抗（抗 CD20）治疗后免疫球蛋白游离轻链减少与疾病活动度降低相关。
Ann Rheum Dis. 2010 Dec;69(12):2137-44. doi: 10.1136/ard.2009.126441. Epub 2010 Aug 2.
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Ig-free light chains play a crucial role in murine mast cell-dependent colitis and are associated with human inflammatory bowel diseases.无免疫球蛋白轻链在小鼠肥大细胞依赖性结肠炎中发挥关键作用，并与人类炎症性肠病相关。
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