Chen Y L
Department of Internal Medicine, Xuan-Wu Hospital, Beijing, People's Republic of China.
J Clin Gastroenterol. 1990 Feb;12(1):63-6. doi: 10.1097/00004836-199002000-00016.
In two patients, frequent retching and vomiting preceded acute upper gastrointestinal hemorrhage. Congestion and edema were limited to the prolapsed portion of the stomach, the cardia, where discrete erosions and small shallow ulcers were seen. At endoscopy, prolapse of the gastric mucosa into the esophageal lumen was quite evident whenever the patients retched. The endoscopic features and pathogenesis of Mallory-Weiss syndrome were readily differentiated. It seemed probable that repeated retching causing intussusception of the cardia of the stomach can mechanically produce gastritis and should be a recognizable cause of acute upper gastrointestinal bleeding. I take this entity to be an independent superficial mucosal disease of the stomach.
在两名患者中,频繁干呕和呕吐先于急性上消化道出血出现。充血和水肿仅限于胃的脱垂部分,即贲门,在该处可见散在的糜烂和小的浅溃疡。在内镜检查时,每当患者干呕时,胃黏膜脱垂入食管腔的情况就非常明显。马洛里-魏斯综合征的内镜特征和发病机制很容易区分。反复干呕导致胃贲门套叠很可能会机械性地引发胃炎,并且应该是急性上消化道出血的一个可识别病因。我认为这个实体是一种独立的胃浅表黏膜疾病。