Inoue Ken, Wakabayashi Naoki, Fukumoto Kohei, Yamada Shinya, Bito Nobukatsu, Yoshida Naohisa, Katada Kazuhiro, Uchiyama Kazuhiko, Ishikawa Takeshi, Handa Osamu, Takagi Tomohisa, Konishi Hideyuki, Yagi Nobuaki, Kokura Satoshi, Kishimoto Mitsuo, Yanagisawa Akio, Naito Yuji
Department of Gastroenterology and Hepatology, Kyoto Prefectural Yosanoumi Hospital, Japan.
Intern Med. 2012;51(19):2739-43. doi: 10.2169/internalmedicine.51.8145. Epub 2012 Oct 1.
Most cases of cytomegalovirus (CMV) colitis in patients with inflammatory bowel disease (IBD) occur in those treated with immunosuppressants and/or corticosteroids. We herein present the case of a 57-year-old man with toxic megacolon associated with CMV colitis in corticosteroid-naïve ulcerative colitis (UC). To date, there have been only eight previous case reports of CMV colitis in steroid-naïve UC. We discuss the need to consider CMV colitis when making a differential diagnosis of patients with refractory UC who are not receiving corticosteroid treatment.
炎症性肠病（IBD）患者中，大多数巨细胞病毒（CMV）结肠炎病例发生在接受免疫抑制剂和/或皮质类固醇治疗的患者中。我们在此报告一例57岁男性，患有与CMV结肠炎相关的中毒性巨结肠，其溃疡性结肠炎（UC）未接受过皮质类固醇治疗。迄今为止，之前仅有8例关于未接受过皮质类固醇治疗的UC患者发生CMV结肠炎的病例报告。我们讨论了在对未接受皮质类固醇治疗的难治性UC患者进行鉴别诊断时，需要考虑CMV结肠炎。
