Tepecik Education and Research Hospital, Department of Gastroenterology, Yenisehir-Izmir, Turkey.
Arch Iran Med. 2019 Feb 1;22(2):99-101.
Cytomegalovirus (CMV) is an agent which exists asymptomatically in most individuals and may cause latent life-time infection following contamination. Symptomatic CMV infection develops most commonly in organ transplant recipients and in individuals who receive immunosuppressive drugs, undergo haemodialysis or have acquired immunodeficiency syndrome. The link between ulcerative colitis and CMV infection and the efficacy of antiviral therapy in these individuals have been demonstrated. Due to the fact that synchronous onset of CMV and ulcerative colitis is a very rare clinical condition, we present here a synchronous-onset fulminant CMV and ulcerative colitis in a 58-year-old man without any other co-morbidities.
巨细胞病毒(CMV)在大多数个体中无症状存在,感染后可能导致潜伏性终身感染。症状性 CMV 感染最常发生于器官移植受者以及接受免疫抑制剂药物治疗、行血液透析或患有获得性免疫缺陷综合征的个体中。已证明溃疡性结肠炎与 CMV 感染之间存在关联,以及抗病毒治疗在这些个体中的疗效。由于 CMV 和溃疡性结肠炎同时发病的情况非常罕见,因此我们在此报告一例 58 岁男性同时发生的暴发性 CMV 和溃疡性结肠炎,且该患者无其他合并症。