Bahri Raoudha, Ben Halima Abir, Ayadi Imen, Esteban Esther, Alfadhli Suad M, Rebai Ahmed, Moral Pedro, Chaabani Hassen
Laboratory of Human Genetics and Anthropology, Faculty of Pharmacy, University of Monastir, Monastir, Tunisia.
Ann Hum Biol. 2013 Jan;40(1):35-40. doi: 10.3109/03014460.2012.728622. Epub 2012 Oct 8.
The genetic differentiation of Bahrain natives is unclear because of the absence of adequate genetic studies.
Eight Alu insertion polymorphisms have been analysed in Bahrainis and southern Iranians to examine the origins of Bahrainis and to determine their genetic position among wider Middle East populations.
Two representative samples of 97 Bahrainis and 65 southern Iranians have been determined. Genetic relationships among populations have been estimated by a principal component plot based on the R-matrix software. Mantel tests have been used to check the statistical significance of correlation between genetic and geographic distances.
The results show that Bahrainis are in an intermediate genetic position between Emirians and Southern Iranians. Although a general significant correlation between genetic and geographic distances was found between the 16 populations included in the analysis, a lack of this correlation may occur in some particular situations such as the case of populations from southern Iran, United Arab Emirates (UAE) and Bahrain, separated by the Persian Gulf.
The results support the idea that Bahrainis ancestors were mainly emigrants from Arabia and Iran. In addition the results show that the Iranian component may reach 69.2% of the current genetic pool of Bahrainis.
由于缺乏充分的基因研究，巴林当地人的基因分化情况尚不清楚。
对巴林人和伊朗南部人进行了8种Alu插入多态性分析，以探究巴林人的起源，并确定他们在更广泛中东人群中的基因位置。
确定了97名巴林人和65名伊朗南部人的两个代表性样本。基于R矩阵软件的主成分图估计了人群之间的基因关系。使用曼特尔检验来检验基因距离与地理距离之间相关性的统计显著性。
结果表明，巴林人在阿联酋人和伊朗南部人之间处于中间基因位置。尽管在分析的16个人群中发现基因距离与地理距离之间总体存在显著相关性，但在某些特定情况下可能不存在这种相关性，例如被波斯湾隔开的伊朗南部、阿拉伯联合酋长国（阿联酋）和巴林的人群。
结果支持巴林人的祖先主要是来自阿拉伯和伊朗的移民这一观点。此外，结果表明伊朗成分可能占巴林人当前基因库的69.2%。
