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贾第虫病合并蛋白丢失性肠病:通过粪便α1-抗胰蛋白酶测定进行诊断。

Giardiasis with protein-losing enteropathy: diagnosis by fecal alpha 1-antitrypsin determination.

作者信息

Korman S H, Bar-Oz B, Mandelberg A, Matoth I

机构信息

Department of Pediatrics, Hadassah University Hospital, Jerusalem, Israel.

出版信息

J Pediatr Gastroenterol Nutr. 1990 Feb;10(2):249-52. doi: 10.1097/00005176-199002000-00019.

Abstract

Giardia lamblia infection was documented by jejunal biopsy in a previously healthy 2-year-old boy with acute onset of hypoproteinemia due to protein-losing enteropathy. All symptoms and abnormal laboratory findings resolved with anti-Giardia therapy. This is only the second case report of giardiasis with documented protein-losing enteropathy. Further application of the fecal alpha 1-antitrypsin assay may help to clarify the relationship between Giardia infection and protein-losing enteropathy and its role in development of malnutrition.

摘要

一名既往健康的2岁男孩因蛋白丢失性肠病急性发作出现低蛋白血症,经空肠活检证实存在蓝氏贾第鞭毛虫感染。抗贾第虫治疗后,所有症状及异常实验室检查结果均消失。这是有记录的蛋白丢失性肠病合并贾第虫病的第二例病例报告。粪便α1-抗胰蛋白酶检测的进一步应用可能有助于阐明贾第虫感染与蛋白丢失性肠病之间的关系及其在营养不良发生中的作用。

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