Perelman School of Medicine, the University of Pennsylvania, Pennsylvania, USA.
Urology. 2012 Dec;80(6):1366-8. doi: 10.1016/j.urology.2012.08.020. Epub 2012 Oct 2.
Ecthyma gangrenosum (EG) is a cutaneous infection most commonly associated with Pseudomonas aeruginosa sepsis. EG generally occurs in immunocompromised hosts, such as patients with severe neutropenia. EG presents as erythematous, hemorrhagic, or necrotic macules or plaques, most commonly in the perineal or gluteal areas, but can occur elsewhere. EG is a dermatologic emergency in immunocompromised patients and should be included in the differential diagnosis when urologists are asked to evaluate perineal lesions. We describe the case of a highly immunocompromised infant with labial EG to highlight the importance of prompt clinical diagnosis and of multidisciplinary medical and surgical management.
坏疽性脓皮病(EG)是一种皮肤感染,最常与铜绿假单胞菌败血症有关。EG 通常发生在免疫功能低下的宿主中,如严重中性粒细胞减少症患者。EG 表现为红斑、出血或坏死性斑疹或斑块,最常见于会阴或臀部区域,但也可能发生在其他部位。EG 是免疫功能低下患者的皮肤科急症,当泌尿科医生被要求评估会阴病变时,应将其纳入鉴别诊断。我们描述了一例高度免疫功能低下婴儿的唇部 EG 病例,以强调及时临床诊断和多学科医疗和手术管理的重要性。