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疑似艰难梭菌相关性腹泻时，用核酸扩增试验替代传统酶免疫分析法的临床影响。

Clinical impact of switching conventional enzyme immunoassay with nucleic acid amplification test for suspected Clostridium difficile-associated diarrhea.

机构信息

Department of Pharmacy Practice, Campbell University College of Pharmacy and Health Sciences, Buies Creek, NC, USA.

出版信息

Am J Infect Control. 2013 Apr;41(4):373-5. doi: 10.1016/j.ajic.2012.04.329. Epub 2012 Oct 5.

DOI:10.1016/j.ajic.2012.04.329
PMID:23040489
Abstract

The impact of a new Clostridium difficile nucleic acid amplification test (NAAT) on antibiotic utilization in patients with suspected C difficile infection was assessed. This single-center, cross-sectional study of 270 patients demonstrated that the use of NAAT decreased antibiotic expenditure by reducing prolonged empiric days of therapy in these patients.

摘要

评估了一种新型艰难梭菌核酸扩增检测（NAAT）对疑似艰难梭菌感染患者抗生素使用的影响。这项对 270 名患者进行的单中心、横断面研究表明，NAAT 的使用通过减少这些患者经验性治疗的延长天数，降低了抗生素支出。

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引用本文的文献

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Effect of nucleic acid amplification testing on population-based incidence rates of Clostridium difficile infection.核酸扩增检测对基于人群的艰难梭菌感染发病率的影响。
Clin Infect Dis. 2013 Nov;57(9):1304-7. doi: 10.1093/cid/cit492. Epub 2013 Jul 29.
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Performance of Clostridium difficile toxin enzyme immunoassay and nucleic acid amplification tests stratified by patient disease severity.按患者疾病严重程度分层的艰难梭菌毒素酶免疫分析和核酸扩增检测的性能。
J Clin Microbiol. 2013 Mar;51(3):869-73. doi: 10.1128/JCM.02970-12. Epub 2012 Dec 26.