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泌乳素瘤的药物治疗与手术治疗。

Medical versus surgical management of prolactinomas.

机构信息

Department of Neurological Surgery, California Center for Pituitary Disorders, University of California, San Francisco, CA 94143, USA.

出版信息

Neurosurg Clin N Am. 2012 Oct;23(4):669-78. doi: 10.1016/j.nec.2012.06.010. Epub 2012 Aug 17.

DOI:10.1016/j.nec.2012.06.010
PMID:23040751
Abstract

Prolactinomas are the most common hormone-secreting pituitary adenomas, comprising 40% of all pituitary tumors. Prolactinomas present a unique challenge for clinicians, as these tumors are amenable to either medical or surgical treatments based on patients' comorbidities, tolerance to medical treatment, and the response of tumors to medical treatment. Rare prolactinomas that are unresponsive to either medical or surgical treatment modalities may be responsive to radiation therapy. This article reviews the recent advancements in the management of prolactinomas.

摘要

催乳素瘤是最常见的激素分泌性垂体腺瘤,占所有垂体肿瘤的 40%。催乳素瘤对临床医生来说是一个独特的挑战,因为这些肿瘤可以根据患者的合并症、对药物治疗的耐受性以及肿瘤对药物治疗的反应,采用药物或手术治疗。对于那些对药物或手术治疗均无反应的罕见催乳素瘤,可能对放射治疗有反应。本文综述了催乳素瘤治疗的最新进展。

相似文献

1
Medical versus surgical management of prolactinomas.泌乳素瘤的药物治疗与手术治疗。
Neurosurg Clin N Am. 2012 Oct;23(4):669-78. doi: 10.1016/j.nec.2012.06.010. Epub 2012 Aug 17.
2
Non-surgical management of hormone-secreting pituitary tumors.激素分泌性垂体瘤的非手术治疗
J Clin Neurosci. 2009 Aug;16(8):985-93. doi: 10.1016/j.jocn.2008.11.001. Epub 2009 May 13.
3
Update in prolactinomas.泌乳素瘤的最新进展。
Neth J Med. 2010 Mar;68(3):104-12.
4
Gamma knife radiosurgery for medically and surgically refractory prolactinomas.伽玛刀放射外科治疗药物和手术难治性泌乳素瘤。
Neurosurgery. 2006 Aug;59(2):255-66; discussion 255-66. doi: 10.1227/01.NEU.0000223445.22938.BD.
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Management of resistant prolactinomas.耐药性泌乳素瘤的管理
Nat Clin Pract Endocrinol Metab. 2006 Oct;2(10):552-61. doi: 10.1038/ncpendmet0290.
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Current approach to treatments for prolactinomas.目前催乳素瘤的治疗方法。
Minerva Endocrinol. 2016 Sep;41(3):316-23. Epub 2015 Sep 24.
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Perspective in pituitary adenomas: an end of the century review of tumorigenesis, diagnosis, and treatment.
Clin Neurosurg. 2000;47:99-111.
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[Prolactinoma].[催乳素瘤]
Przegl Lek. 2009;66(4):198-205.
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Contemporary management of prolactinomas.催乳素瘤的当代管理
Neurosurg Focus. 2004 Apr 15;16(4):E2. doi: 10.3171/foc.2004.16.4.3.
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引用本文的文献

1
The Chance of Permanent Cure for Micro- and Macroprolactinomas, Medication or Surgery? A Systematic Review and Meta-Analysis.微泌乳素瘤和大泌乳素瘤的永久治愈几率:药物治疗还是手术治疗?一项系统评价与荟萃分析
Front Endocrinol (Lausanne). 2018 Oct 25;9:636. doi: 10.3389/fendo.2018.00636. eCollection 2018.
2
Cost-Effectiveness Analysis of Surgical versus Medical Treatment of Prolactinomas.泌乳素瘤手术治疗与药物治疗的成本效益分析
J Neurol Surg B Skull Base. 2017 Apr;78(2):125-131. doi: 10.1055/s-0036-1592193. Epub 2016 Sep 27.
3
Gamma Knife radiosurgery for medically and surgically refractory prolactinomas: long-term results.
伽玛刀放射外科治疗药物和手术难治性泌乳素瘤:长期结果
Pituitary. 2015 Dec;18(6):820-30. doi: 10.1007/s11102-015-0658-1.
4
Early prediction of long-term response to cabergoline in patients with macroprolactinomas.大泌乳素瘤患者卡麦角林长期反应的早期预测。
Endocrinol Metab (Seoul). 2014 Sep;29(3):280-92. doi: 10.3803/EnM.2014.29.3.280. Epub 2014 Sep 25.